Neuchatel, Switzerland


Life Sciences



Job ID


Manager In vitro screening and organotypic research – Neuchatel, Switzerland Be a part of a revolutionary change! At PMI, we’ve chosen to do something incredible. We’re totally transforming our business, and building our future on smoke-free products with the power to improve the lives of a billion smokers worldwide. With huge change, comes huge opportunity. So, wherever you join us, you’ll enjoy the freedom to dream up and deliver better, brighter solutions and the space to move your career forward in endlessly different directions. It’s so rare in R&D that everything aligns to create the ideal conditions for outstanding work. Right now, at PMI, that’s exactly what’s happening. R&D is the driving force for our bold new vision: to replace cigarettes with a revolutionary portfolio of alternative products. Join us and you’ll have the resources, support and technology you need to break new ground and see ideas come to life. You’ll be surrounded by some of the brightest scientists in their fields, with fast access to subject experts and commercial decision-makers. If you’re creative, courageous and ready to take risks, you can make a huge impact and propel your career in an endless number of directions. Ultimately, by delivering our smoke-free future, your work could change the lives of a billion smokers. Your ‘day to day’ As a Manager In vitro screening and organotypic research you'll be accountable for directing a group of in vitro scientists and lab technician to achieve departmental objectives towards the assessment of RRPs and beyond nicotine products, utilizing non-regulatory in vitro test systems and procedures. You'll be managing the activities for in vitro safety/efficacy studies in the context of 2D (High-content screening) and 3D (whole aerosol) cell culture systems. You will prepare and adapt the roadmap to accommodate in vitro studies according to the needs from Life Science Categories, Disease Biology and Systems Toxicology and upon prioritization by Experimental Biology project management. You will keep the portfolio of test systems and methods state-of-the-art, by continuous development of team member skills base and following the developments in the in vitro model system arena. . More specifically, you'll • Be responsible for a portfolio of preclinical activities aimed at supporting the toxicological assessment of new products by leading and coordinating the activity of laboratories within the In vitro pharmacology group. • In collaboration with the Assay Development Team, establish and handle a portfolio of screening activities aimed at supporting discovery campaigns through various strategic work packages. • Supervise and develop a team including scientists, and lab technicians. • Collaborate as SME with Study Directors to define optimal study designs to answer key scientific questions. • Support innovation and exploration into novel cutting edge methods to optimize, improve and expand the laboratory portfolio. Increase laboratory performances by leading automation initiatives. • Write proposals and generating presentations for project teams and leadership meetings. • Represent In vitro pharmacology research internally and externally. • Contribute to manuscripts for publication and present work at scientific meetings. • Establish collaborations with specialists in the field to keep abreast of the latest available technologies. Who we’re looking for • MSc and or PhD in relevant biology areas with a good track record of accomplishments characterizing cellular responses. • Substantial experience leading a scientific research team in an academic or industry setting including leading projects, research teams and serving as a mentor. • Demonstrated knowledge in relevant biological areas including cell biology, toxicology, pharmacology. • Sound technical expertise in cell culture, imaging, high-throughput assays, and lab automation. • Good know-how in the early R&D phases of drug discovery and a deep understanding of the requirements for projects to progress through target assessment, lead identification and lead optimization to candidate selection in a multidisciplinary environment. • Confirmed track record in leadership, ideally leading in a matrix organization with validate ability to generate results and align organizational resources to accomplish strategic objectives. • Excellent communication skills and ability to express complex concepts at all levels of the organization, encourage direct and open discussions, seek common ground in to resolve conflicts set-up. • Fluent, well written and spoken English is mandatory. What we offer Our success depends on the men and women who come to work every single day with a sense of purpose and an appetite for progress. Join PMI and you too can: • Seize the freedom to define your future and ours. We’ll empower you to take risks, experiment and explore. • Be part of an inclusive, diverse culture, where everyone’s contribution is respected; collaborate with some of the world’s best people and feel like you belong. • Pursue your ambitions and develop your skills with a global business – our staggering size and scale provides endless opportunities to progress. • Take pride in delivering our promise to society: to improve the lives of a billion smokers. #LIJobs