Neuchatel, Switzerland


Life Sciences



Job ID


Scientist Smoke-Free Product & Nicotine Science – Neuchâtel, Switzerland Be a part of a revolutionary change. At PMI, we’ve chosen to do something incredible. We’re totally transforming our business, and building our future on smoke-free products. With huge change, comes huge opportunity. So, wherever you join us, you’ll enjoy the freedom to dream up and deliver better, brighter solutions and the space to move your career forward in endlessly different directions. It’s so rare in R&D that everything aligns to create the ideal conditions for outstanding work. Right now, at PMI, that’s exactly what’s happening. R&D is the driving force for our bold new vision: to replace cigarettes with a revolutionary portfolio of alternative products. Join us and you’ll have the resources, support and technology you need to break new ground and see ideas come to life. You’ll be surrounded by some of the brightest scientists in their fields, with fast access to subject experts and commercial decision-makers. If you’re creative, courageous and ready to take risks, you can make a huge impact and propel your career in an endless number of directions. Ultimately, by delivering our smoke-free and beyond nicotine future. Your ‘day to day’ As a Scientist Smoke-Free Product (SFP) & Nicotine Science you will be accountable for delivering against the preclinical assessment strategies in support of the SFP and/or the Nicotine Science program. You will plan, design, and implement regulatory toxicology and in vitro alternative toxicology studies to generate data in support of product market launches, engage with other functional units (e.g., the labs) to ensure data and study quality standards are met, serve as a technical resource for in vitro testing, including optimal experimental design and troubleshooting, and also contribute to the execution of the preclinical work packages of the Nicotine Science Risk workstream, in alignment with the program's objectives and based on best knowledge, critically evaluates and reports study findings internally and externally. More specifically, you'll • Conduct preclinical product assessment studies in alignment with the preclinical assessment strategies and the goals of the SFP and/or Nicotine Science programs. Act as a Study Director (SD) by planning, designing and coordinating the execution of studies. Collaborate with internally with Test Item Management, Lab Coordinator, Business Manager etc. and oversee study progress to ensure delivery against plan (in time). Critically evaluate and report study findings. • Serve as scientific/technical resource to Product Safety Assessment Leads and SFP Program Leads to develop adequate assessment plans in line with regulatory and quality requirements and enable integration of novel alternative methodologies into assessment strategies for product testing. • Collaborate as scientific/technical resource to Lab Manager to develop and maintain adequate testing environment (e.g., data and study quality) as well as adequate proficiency level of lab staff. Ensure Quality Management Principles are being established, maintained or updated when needed and followed. • Work as scientific/technical resource to Product Safety Assessment Leads to monitor planning, execution and reporting of outsourced preclinical product assessment studies. Collaborate to supervise vendor/service supplier relationship. Oversee progress against plan, review and evaluate deliverables and provide recommendations to Product Safety Assessment Leads for use/integration of externally generated data in support of market launches. • Contribute to the establishment of novel alternative methodologies as part of integrated assessment strategies under the umbrella of 21st Century Toxicology in collaboration with other functional units (e.g., the labs). Act as a Study Director (SD) by planning, designing and coordinating the execution of feasibility, validation and testing studies as needed. Contribute to the planning and execution of preclinical work packages of the Nicotine Science program where and when needed. Engage key opinion leaders (KOLs) to oversee and coordinate execution of external studies. Provide critical review of study findings, and help to articulate messages in support of the program's communication plan. Ensure Quality Management Principles are being established, maintained or updated when needed, and followed. Who we’re looking for • Master’s Degree in Science or PhD in Molecular and Cellular Biology or related field. • Demonstrated post-graduate experience, either in academic or industry environment, product safety assessment experience preferred • Understanding of toxicology and product assessment strategies • Sound knowledge of GLP and ISO processes • Familiarity with product categories and (systems) biological approaches to toxicology • Skilled in scientific writing/reporting • Fluent in written and verbal English. What we offer Our success depends on the people who come to work every single day with a sense of purpose and an appetite for progress. Join PMI and you too can: • Seize the freedom to define your future and ours. We’ll empower you to take risks, experiment and explore. • Be part of an inclusive, diverse culture, where everyone’s contribution is respected; collaborate with some of the world’s best people and feel like you belong. • Pursue your ambitions and develop your skills with a global business – our staggering size and scale provides endless opportunities to progress. • Take pride in delivering our promise to society: a smoke-free future. #LIJobs